Clone Screening

Dedicated solutions for clone screening and single cell isolation

  • Improved probability of finding rare clones of interest
  • Objective selection of mammalian clones and microbial colonies
  • Proven techniques for establishing monoclonality

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Clone screening systems for monoclonality verification and colony picking

Our solutions for antibody discovery and cell line development provide dedicated, scalable, and easy-to-use products for establishing clonal populations. The systems feature a selection of options and models to address your specific research including multiple imaging modes, biology-specific pins, fluidics, and environmental control. These solutions combine intelligent imaging with analysis and automation to increase throughput, consistency, and provide image-based documentation.

Verify monoclonality easily

Objective selection, imaging, and data collection streamlines tracking of colony formation from a single cell.

Sort viable single cells efficiently

High accuracy robotics combined with gentle fluidics-based systems establish viable clones with much higher efficiency.

Streamline workflows

Automation with sample tracking increases throughput, allows for more walk-away time, and provides consistent results.

Introducing DispenCell Single-Cell Dispenser

QPix 400 Series

Fully automate synthetic biology workflows for DNA assembly, antibody discovery and protein engineering

The QPix® 400 Series Microbial Colony Pickers combine intelligent image analysis with precise automation for fast and efficient screening of large libraries. With a variety of data tracking and assay tools, the QPix Software streamlines the control and management of complex and iterative processes.

QPix 400 Series
  • Automate several sample prep and plate handling processes such as transfer of bacterial liquid culture and plating on agar
  • Streamline your workflow with scalable automation – pick up to 30,000 colonies per day
  • Electronic data tracking for well-documented data control
  • Sterile environment with customizable HEPA filtration options

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ClonePix Series

Automate antibody discovery and cell line development workflows

Screen more clones with the ClonePix® Series in less time with monoclonal verification on day zero, then screen and pick for highest producers in weeks, not months.

ClonePix Series
  • Screen 10X more clones than limiting dilution
  • Increase probability of identifying high-value clones
  • Condense the workflow into a single solution
  • Eliminate or recover unstable clones early

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CloneSelect Imager and CloneSelect Imager FL

Verify monoclonality confidently

The all-new CloneSelect Imager FL adds high contrast multichannel fluorescent technology in addition to the standard white light imaging that allows for accurate single-cell detection and proof of monoclonality at day 0. Streamline your workflow with comparative confluence assays to identify and verify gene edits.

CloneSelect Imager FL
  • Document evidence of single cells and confluency digitally for auditing and submission to regulatory authorities
  • Image cells non invasively at multiple time points to monitor colony formation
  • Screen using high resolution white light imaging
  • Deliver real-time results with on-the-fly analysis
  • Automation and integration ready

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DispenCell™ Single-Cell Dispenser

A simple single-cell dispenser for proof of monoclonality

The DispenCell Single-Cell Dispenser is an automated laboratory instrument designed for fast, easy, and gentle single-cell isolation. Cell dispensing technology enables scientists to isolate single cell lines three times faster and at a lower cost compared to existing solutions.

DispenCell Single-Cell Dispenser
  • Easy, intuitive setup with no cleaning or calibration required
  • Software that provides instantaneous proof of clonality and traceability post cell dispensing
  • Unique technology gently handles the cell sample for better viability and cloning efficiency compared to manual pipetting
  • Benchtop-size designed to fit under a hood, on a bench, or in a pre-existing automated workflow
  • A patented disposable tip to ensure clean isolation of single cells and no cross-contamination, which is certified free from animal products and cytotoxic material

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Applications & Research

Find an extensive collection of application notes, research, and workflows related to clone screening including cell line development, antibody discovery, and more.

View our complete line of clone screening systems along with an assortment of high-performance media and labware. We also offer services for instrument customizations and robotics.

How can we help advance your next big discovery?

Our highly-qualified teams are on the frontlines with our customers, conducting remote or on-site product demonstrations, webinars, and more to help you solve your tough research challenges. How can we help you today?

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