Dated: Jan 19, 2023
Publication Name: Justyna Gogola-Mruk
Citations : Visfatin induces ovarian cancer resistance to anoikis by regulating mitochondrial activity
Ovarian cancer is characterized by recurrent peritoneal and distant metastasis. To survive in a non-adherent state, floating ovarian cancer spheroids develop mechanisms to resist anoikis. Moreover, ascitic fluid from ovarian cancer patients contains high levels of visfatin with anti-apoptotic properties. However, the mechanism by which visfatin induces anoikis resistance in ovarian cancer spheroids remains unknown. Here, we aimed to assess wheather visfatin which possess anti-apoptotic properties can induce resistance of anoikis in ovarian cancer spheroids.
Contributors: Justyna Gogola-Mruk, Wacław Tworzydło, Kinga Krawczyk, Weronika Marynowicz & Anna Ptak Endocrine