Neuron 3D model

3D neuronal cultures are recognized as more closely recapitulating aspects of the human tissues including the architecture, cell organization, as well as cell-cell and cell-matrix interactions.

Establishment of physiologically-relevant in vitro models is crucial to further understanding of the mechanisms of neurological diseases as well as targeted drug development. While iPSC-derived neurons show great promise for compound screening and disease modeling, use of three-dimensional (3D) cultures is emerging as a valid approach for neuronal cell based assay development.

• Functional and mechanistic neurotoxicity profiling using 3D neural cultures
• Neuronal development in 3D matrix
• Morphological characterization of 3D neuronal networks in a microfluidic platform
• 3D neurospheroid for high-throughput screening