Assay Kit Mechanism

EarlyTox Cell Integrity Kit uses two nuclear dyes that allow users to detect changes in outer cell membrane permeability resulting from cell damage or cell death via necrosis, apoptosis, or other mechanism. Cell viability is assessed by counting the number or percent of live and damaged cells. The assay can be used for studies of the effects of different treatments on cell viability, evaluation of toxicity effects of pharmaceutical compounds or other chemicals, studies of necrosis and apoptosis, and many other applications.